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In patients with HFpEF and obesity, both semaglutide (STEP-HFpEF) and tirzepatide (SUMMIT) significantly reduced cardiovascular death and worsening heart failure events, with concomitant improvements in quality of life and functional capacity [3,47]

According to the Center for Disease Control and Prevention (CDC), 38.4 million Americans (12% of the population) have diabetes

(4) S Doessing, L Holm, K M Heinemeier, U Feldt-Rasmussen, et al (2010) GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients European Journal of Endocrinology, 2010 Dec, Volume 163 (Issue 6), Pages 853-62

124,142 Investigations into mechanism of action-mediated pharmacokinetic DDIs are currently limited to those mediated by the slowing of gastric emptying, with examples summarized in other reviews