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He also highlighted polyphenol-rich foods such as extra virgin olive oil, green tea, and even coffee as helpful for the microbiome

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Important unresolved questions include whether BPC-157 reaches relevant central compartments under specific experimental conditions, whether observed CNS model effects depend primarily on vascular preservation, whether neurotransmitter changes are primary or secondary, and whether the brain-gut-axis hypothesis can be separated experimentally from general systemic effects