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The authors concluded that GHK and GHK-Cu increased epidermal cell stemness and keratinocyte proliferation, also increasing p63 and integrin expression [ 48 , 49 ]

Interstitial Cystitis/Bladder Pain Syndrome is defined as An unpleasant sensation (pain, pressure, discomfort) perceived to be related to the urinary bladder, associated with lower urinary tract symptoms of more than six weeks duration, in the absence of infection or other identifiable causes. An unpleasant sensation (pain, pressure, discomfort) perceived to be related to the urinary bladder, associated with lower urinary tract symptoms of more than six weeks duration, in the absence of infection or other identifiable causes. Over the years, this diagnosis has changed dramatically from how it is defined to approaching treatment

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