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Management options may include dose adjustment, additional support for managing gastrointestinal side effects, referral to diabetes psychology services, or consideration of alternative diabetes medications if symptoms are genuinely medication-related and problematic

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Hyperglycaemia progressively impairs these transporters, accelerating beta-cell apoptosis and microvascular complications

These structures termed liposomes have the ability to protect Setria from both the action of hydrolytic enzymes and premature oxidation but also to promote fusion with the enterocyte cell membrane thereby increasing intracellular concentration