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However, the reversed effect of semaglutide on cardiac hypertrophy was abolished by HCQ, which restored the activation of NLRP3 inflammasome suppressed by improved mitophagy
The three-way comparison between semaglutide, tirzepatide, and retatrutide provides additional context
N Engl J Med 321:580585 Schtten MTJ, Houben AJHM, de Leeuw PW, Stehouwer CDA (2017) The link between adipose tissue renin-angiotensin-aldosterone system signaling and obesity-associated hypertension
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