THERAPEUTIC TARGETING OF DNA-PKCS WITH M3814 IN COMBINATION WITH CPX-351 (VYXEOS) ACHIEVES PROFOUND LEUKEMIA REDUCTION IN TP53WT AND TP53MUT ACUTE MYELOID LEUKEMIA
VHE is typically characterized by acute onset of impaired consciousness, focal neurologic symptoms and increased seizure frequency [69]
Richard Horowitz describes the Jarisch-Herxheimer (JH) flare as a temporary worsening of the symptoms of Lyme disease that occurs when the Lyme spirochete is being killed off by antibiotics, creating inflammationThese JH reactions produce cytokines (TNF-alpha, IL-6, and IL-8), which then create inflammatory symptoms, including increased fever, muscle and joint pain, headaches, cognitive impairment, and a general worsening of the underlying symptomology
About this article Cite this article Desai, A., Khataniar, H., Tabaku, F