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For the efficacy-evaluable population, the group of patients treated with ALC showed a significantly greater reduction in pain, compared to the placebo group

[23] In the diseased brain, GLP-1 receptor agonist treatment is associated with protection against a range of experimental disease models such as Parkinson's disease, [24] [18] Alzheimer's disease, [25] [26] stroke, [24] traumatic brain injury, [14] [19] and multiple sclerosis

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Studies have shown that Complex I activity is diminished in both post-mortem brain tissue and peripheral blood cells of PD patients (38, 39)