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PloS One (2021) 16(5):e0251642
However, it remains unclear whether GLP-1 therapy would provide meaningful clinical benefit for RA-specific outcomes such as joint damage progression, functional status, or quality of life in patients without concurrent diabetes or obesity
However, according to the Liraglutide Effect and Action in Diabetes (LEAD) the reduction in systolic blood pressure of 3.6-6.7mmHg occurred within 2 weeks, which resulted prior to any substantial weight loss, this effect lasted throughout the entire 26-week trial 7
Over the next few months, you'll gradually increase to 4 mg , then 9 mg , and finally to the 25 mg maintenance dose to help your body adjust comfortably
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