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This was done using a sandwich ELISA assay which employed a purified antibody to collagen type I

Association of vitamin B12 deficiency in people with type 2 diabetes on metformin and diabetic peripheral neuropathy Nature article: Shows prolonged metformin use correlates with lower B12 and more severe diabetic neuropathy

I usually pair it with metabolic basics: continuous glucose monitoring if appropriate, structured protein intake, and a structured resistance training program

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