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Further studies have explored antioxidant effects , immune modulation , and gene expression pathways linked to aging and oxidative stress

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Sex as a biological variable: we utilized only male rats to maximize the satellite cell yield per gram of muscle tissue and individual animal (Figure 1d,f and supplementary Figure 1a) and male mice to examine the preventive effect of oral administration of glutathione trisulfide (GSSSG) and lipoic acid trisulfide (LASSS) (Figure 2e) on disuse-induced nitration-dysfunction of ECM-bound HGF