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Severe Gastrointestinal Disease: Zepbound is associated with gastrointestinal side effects, such as nausea, diarrhea, vomiting, constipation, and stomach pain, and can sometimes be severe
To improve transparency, Supplementary Table 7 summarizes molecule-specific pharmacokinetic and clinical considerations, including approximate half-life, label-informed discontinuation or washout recommendations before planned conception, representative human pregnancy-exposure evidence, reported adverse outcomes, and an interpretive certainty judgment
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