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It occurs naturally in human plasma, saliva, and urine, and its plasma concentration declines significantly with age, from approximately 200 ng/mL in young adults to much lower levels in older individuals
It is recommended that Berberine be taken with food and if possible use gastroprotective coated formulations
Yoon S, Han SS, Rana SV
In clinical practice, it is common to see frustrated patients who tried oral or sublingual versions without noticing any changes in body composition, energy levels, or sleep quality
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