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These systems enhance ocular permeability, prolong drug residence time, improve physicochemical stability, and significantly increase bioavailability, thereby addressing the critical challenges associated with natural product delivery and paving the way for more effective and targeted ocular therapies [348, 349]
Although water-referenced neurochemical concentrations are considered by some as the gold standard approach for MRS, there are numerous technical challenges and assumptions that can limit the utility of water-referenced measurements
Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo
On the other hand, the treatment policity estimand was used to evaluate the treatment effect for all randomized participants regardless of whether the trial was discontinued early or rescue medicien was used [2]
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