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Microdosing modifies one or more elements of that pattern: Starting below 2.5 mg using specialized preparations under medical supervision, Stretching each titration step to many more weeks Choosing an intermediate maintenance dose, such as 5 mg or 7.5 mg, rather than escalating to 1015 mg Altering the injection frequency to smooth exposure

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As the global prevalence of AD continues to rise, especially among postmenopausal women, dual agonism targeting estrogen and GLP-1 receptors may represent a novel, physiologically informed approach to prevention and intervention

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