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Researchers followed 173 patients with rheumatoid arthritis and a BMI of at least 27 who took semaglutide or tirzepatide, compared with 42 who were prescribed the medication but never started it

Biomarker Context and Dosing Response Variability Dosing efficacy varies significantly across individuals due to differences in metabolic rate, insulin sensitivity, glucagon-like peptide-1 receptor expression, and gastrointestinal motility