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I think we are going to have a long term patient-doctor relationship. - Cor E., Portland, OR

Many experienced users report optimal outcomes in the 0.25mg to 0.5mg range, with diminishing returns above that level

Induction of phase II detoxifying enzymes Many isothiocyanates are potent inducers of phase II detoxifying enzymes, including GSTs, UDP-glucuronosyl transferases (UGTs), NQO1, and glutamate cysteine ligase (GCL), that protect cells from DNA damage by carcinogens and reactive oxygen species (ROS) (25)

Staying well-hydrated is crucial, particularly if experiencing vomiting or diarrhea, though large volumes of fluid with meals should be avoided as this may worsen symptoms