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This accumulation dampens IFNB1-mediated signaling, reducing activation of downstream transcription factors signal transducer and activator of transcription 1 (STAT1), STAT2, and IFN-stimulated genes
[1] The Role of NAC in Hashimotos and Liver Support Those with Hashimotos often have an impaired ability to clear toxins and may have an overload or accumulation of toxins
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