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Reversal of diet-induced obesity in mice The defining study, Neelakantan and colleagues in Biochemical Pharmacology (2018), reported that a potent methylquinolinium NNMT inhibitor reduced body weight, white-fat mass, adipocyte size and plasma cholesterol in diet-induced obese mice, without changing food intake or causing overt adverse findings [1]

They may slightly reduce hunger (since growth hormone can influence appetite signals), but their key effect is improving metabolism and body composition rather than making you eat less

Preclinical work in obese murine models suggests that encapsulated 5-Amino-1MQ administration led to decreases in overall body weight and reductions in white adipose mass

Rotate injection sites: Alternate between thighs or arms to avoid irritation or scar tissue