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Were still not sure what the maintenance models will look like: possibly less frequent dosing
Sustained signaling by internalized GLP-1Rs has been reported, but without increasing insulin release 10
Plateaus are part of how the body protects itself during weight loss
There is also evidence that GLP-1RA (such as Lira, etc.) can significantly reduce food intake and promote fatty acid oxidation, thus promoting weight loss and fat mass reduction [16,96]
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