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Acetyl-CoA is the primary substrate for the tricarboxylic acid cycle in mitochondria and modulates the reserves of free CoA which is essential to the function of the tricarboxylic acid cycle
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The two therapies do not share metabolic pathways or compete for the same receptors, so combining them does not create pharmacological conflicts
But according to the ODS, research has found only a possible modest reduction in body weight from taking carnitine
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