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Administration Differences TB-500 distributes systemically regardless of injection location due to its low molecular weight and long half-life

Diarrhea affects a similar percentage and sometimes alternates with constipation

Notably, elevated prefrontal GABA levels in PTSD patients are associated with impaired cerebral blood flow (CBF) and symptom severity, normalizing with recovery, highlighting GABA dysregulation as a key mechanism in the disorder