Improved Psychological Well-Being Weight loss can lead to enhanced self-esteem, better body image, and improved mental health
Sources [1] Wilding JPH et al., Diabetes, Obesity and Metabolism, "Weight regain and cardiometabolic effects after withdrawal of semaglutide: the STEP 1 trial extension", [2] Aronne LJ et al., JAMA, "Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial", [3] Electronic Medicines Compendium (eMC), "Mounjaro 2.5 mg solution for injection: Summary of Product Characteristics" (Eli Lilly), [4] Electronic Medicines Compendium (eMC), "Wegovy 0.25 mg2.4 mg solution for injection: Summary of Product Characteristics" (Novo Nordisk), 1 comment Hi, Great overview its reassuring to know that restarting GLP-1 treatment often requires a careful dose adjustment rather than simply picking up where you left off
Another study noted that MOTS-c improved muscle insulin sensitivity and prevented weight gain in mice fed a high-fat diet
This control experiment revealed that ATP retained its ability to mobilize Ca 2+ even when the extracellular Ca 2+ was set to 100 nM (c.f., Fig