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Structurally similar to insulin, this IGF-1 LR3 has the potential primarily to regulate cell tissue growth and development

GLP-1R signaling in the brain exerts antidepressive effects by improving cognitive processes, promoting neuroprotection and neurotransmitter release Patients suffering from depression are characterized by impaired neuronal activity and synaptic plasticity dysfunction, resulting in volumetric changes in brain regions which regulate emotions or the stress response such as the hippocampus and the prefrontal cortex

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10.1136/bmj.k1497 40 YangB.LiS.ChenZ.FengF.HeL.LiuB.et al (2020)