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The study found that the effect of melatonin was not due to the melatonin receptors but rather acts in a receptor-independent manner to clear amyloid-beta plaque.[ref] In addition to clearing amyloid-beta plaque, another way that melatonin can protect against Alzheimers is through the reduction of ROS in the mitochondria in brain cells.[ref] This may be the key, rather than amyloid-beta clearance

Medical guidance is especially important for people with chronic disease, medication use, hormone-sensitive conditions, active malignancy, bleeding disorders, or competitive-sport obligations

But thatsI do strongly believe in a food first, pharma last approach

Its also linked in certain studies to lowered cholesterol levels, although studies have found mixed results regarding all of these effects