Zhang L, Zhang L, Li L, Hlscher C
King to VTA: FDA has no enforcement discretion policy for TDN or NTN products VTA received a letter from Director King on February 2, 2023 outlining CTPs formal position on enforcement discretion regarding tobacco-derived nicotine (TDN) and non-tobacco/synthetic nicotine (NTN) products
They also slow the digestion process, making you feel satiated (full) longer and less compelled to snack in between meals
Phase 2 trial (NEJM, 2023) The landmark Phase 2 trial, published in the New England Journal of Medicine, randomized 338 adults with obesity to receive weekly subcutaneous retatrutide at doses of 1 mg, 4 mg, 8 mg, or 12 mg, or placebo, for 48 weeks