Month 4: Steady Progress (1 mg dose) Average weight loss: 6-8% cumulative (12-16 pounds for a 200-pound person) Around week 12-16, your provider will increase your dose to 1 mg weekly

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Together they suppress appetite and improve glycemic control more strongly than either arm alone but that combined pull on the gut is also the reason someone who starts at a maintenance dose typically feels wretched
However, the rise of compounded GLP-1s comes with serious safety and regulatory concerns