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6-8 weeks for visible results with daily topical application
Intramuscular B12 injections produce faster results than oral supplementation, with reticulocytosis typically beginning by day 34 of treatment
In the semaglutide group, there was an improvement in quality of life according to the Kansas City Cardiomyopathy Questionnaire (KCCQ-CSS), with a mean change in KCCQ-CSS score of 13.7 points with semaglutide and 6.4 points with placebo (p 1% significantly decreased hospitalisations (aOR 1.33
But, there is not enough understanding about the complete effect of extended and repeated use for many years
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