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This effect increases circulation to the extremities, and patients often notice an increase in the warmth of their hands and feet
Biochim Biophys Acta 2012
j , Annexin-V/ Propidium Iodide (A/ PI) staining in cells treated for 24 h
This creates a dangerous bottleneck where highly toxic Phase I intermediates accumulate in the liver, leading to systemic toxicity, severe hepatic inflammation, and a cascading failure of the body's natural waste-removal systems
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