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Nat Rev Drug Discov 9(3):215236 Guengerich FP (2011) Mechanisms of drug toxicity and relevance to pharmaceutical development
It directly and indirectly influences key processes such as metabolic pathways, DNA repair, chromatin remodeling, cellular senescence, and immune cell function
Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease
The assay buffer consisted of DMEM without phenol red (Gibco #11880-028) supplemented with 10 mM HEPES (Gibco #15630-056), 1X GlutaMAX (Gibco #35020-038), and 1% (w/v) ovalbumin (Sigma A5503), 0.1% (v/v) Pluronic F-68 (Gibco, #24040-032)
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