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The dosing schedule should be determined by a healthcare provider, with periodic monitoring of vitamin B levels and clinical symptoms to adjust therapy as needed

Limitations of the study However, the study warns that it has several limitations

Folate and folic acid are forms of vitamin B9 that support healthy cell growth and development, especially in pregnancy

18 Prevention Because of potential interactions from prolonged medication use, physicians should consider screening patients for vitamin B 12 deficiency if they have been taking proton pump inhibitors or H 2 blockers for more than 12 months, or metformin for more than four months