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The combined effect of these modifications increase the drugs half-life from minutes to approximately 168 hours, enabling its once-weekly injection schedule an enormous improvement compared to the twice daily injection required for exenatide (Byetta) which was the first GLP-1 drug that was launched
This mechanism is the reason Bremelanotide became FDA-approved specifically for female sexual interest/arousal disorder (FSIAD)
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Ninety healthy individuals were enrolled in this study
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