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Source record 1997 rat study of BPC-157, nitric-oxide manipulation and blood pressure 2020 isolated rat-aorta and endothelial-signaling study 2021 monocrotaline pulmonary-hypertension study in rats 2001 portal-hypertension study in alcohol-exposed rats 2025 two-person intravenous safety pilot FDAs May 2026 BPC-157 evidence evaluation Registered oral Phase 1 study with no posted results 2025 U.S