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This is a normal response and nothing to worry about
Damian Holsinger, The University of Sydney, Australia Reviewed by Dongwei Sun, University of California, Riverside, United States Tianlong Liu, The 940th Hospital of Joint Logistic Support Force of PLA, China Updates Copyright 2025 Zhu, Ge, Cao, Xiao and Deng
In the multiple-dose trial, semaglutide exposure was approximately twofold higher with 40 versus 20 mg oral semaglutide in healthy males, in accordance with dose proportionality, and was similar between healthy males and males with T2D
Current evidence doesnt point to a specific causal relationship that directly links GLP-1 drugs and microbial overgrowths, but the underlying mechanics and possible resulting effects certainly warrant a degree of caution
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