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Pros: One of the most extensively studied healing peptides in animal and in vitro models, with a broad published mechanistic literature Reported to have a favorable short-term tolerability profile in the limited human data available, with side effects typically mild and self-limiting Available in both injectable and oral research formulations, offering flexibility for different use cases Cons: No completed Phase 2 or Phase 3 human clinical trials exist

Clinical features such as fatigue, paraesthesia, glossitis, and cognitive changes support the diagnosis

The loose stools are generally self-limiting and resolve as the body adjusts to supplementation

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