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A complex puzzle Gloyns team first observed GLP-1 resistance nearly 10 years ago, before the explosion of interest in GLP-1 receptor agonists as weight-loss drugs

The first (experimental) problem that has been clearly identified recently is that most of the AD models used in experimental studies are not clinically valid and therefore cannot be adequately translated into the clinic

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Avoid selfsourcing, untested vials, and multimonth cycles without medical monitoring