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This elevated pressure can overcome the lower esophageal sphincter, the valve between the esophagus and stomach, pushing acid and partially digested food back up
Your first point of contact for any concerns about your trial medication should be your trial team , who are best placed to assess whether symptoms may be related to the investigational medicine and to advise on next steps
The serious adverse event profile appears broadly similar to other incretin-based therapies, but with the addition of glucagon-related effects
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