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As dimeric CBS 516525 behaves almost like full-length (i.e., is active and SAM responsive), a small molecule that disrupts CBS polymerisation and reduces aggregation could be a potential therapeutic avenue for the treatment of HCU (Fig
At the early stage of prediabetes, the OGTT results demonstrated that the insulin exhaustion appeared in the second phase of insulin release
Life sciences 65 , 18651874 (1999)
When a drug binds extensively to components outside the plasma, such as proteins in muscle or lipids in adipose tissue, only a small fraction of the total drug in the body remains in the plasma to be measured
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