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The most common side effects are gastrointestinal including nausea, vomiting, and diarrhoea and are most pronounced during dose increases

By 48 weeks, significant average weight loss was seen at all maintenance doses: With longer treatment lasting up to 68 weeks, weight loss continued, particularly at higher doses: 12mg: average weight loss of up to 28.7% of body weight This longer-term data shows that weight loss with retatrutide can continue beyond one year, rather than plateauing early, especially at higher maintenance doses

Glycemic improvements in patients with type 2 diabetes occur relatively quickly, with fasting glucose reductions often observable within the first week and hemoglobin A1c improvements becoming apparent over 812 weeks

Then the ambulance arrived and they rushed me to hospital, she said