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It is a physiological shift driven by hormonal changes, metabolic slowdown, and changing body composition
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In the absence of MPC activity, import of pyruvate into the mitochondria is greatly diminished, meaning that less acetyl-CoA can be produced by pyruvate dehydrogenase and therefore that TCA cycle flux is diminished (Gray et al., 2015
Your risk for getting low blood sugar may be higher if you use Ozempic with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin
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