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Tolerance and bodily reaction can be considered as doctors track a patients dosage rise

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Clinical trials suggest people eat fewer calories while on semaglutide, with many showing a reduced desire for high-fat meals

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We based the sample size for the trial on an assumed annual primary-event rate of 1.98% in each group, a dropout rate of less than 10.0%, a mean in-trial observation time of 2.1 years, and a true hazard ratio of 1.00

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In fact, due to cost and insurance hurdles, only a small fraction of people who could benefit from these medications are actually prescribed them

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