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doi: 10.1159/000360010 269 WuI
It is a condition in which the bodys response to a drug is lost after repeated exposure and requires higher doses to achieve the desired effects [5]
Results from the co-treatment with Fer1, a ferroptosis inhibitor, and ZVAD, an apoptosis inhibitor, indicate that RSL3 effects were reversed by Fer1 but not by anti-apoptotic ZVAD
We are currently exploring cationic or neutral water solubilizing groups to replace the carboxylic acids in RT to achieve higher temporal resolution while maintaining homogeneous cellular distribution, which will be reported in the due course
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