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Specifically, on day 5, the RGD-GHK group reduced the wound area by approximately 60.9% compared to day 0 (Figure 7F)
55 Epigenetic reprogramming, including DNA methylation and histone modifications, as well as noncoding RNAs (e.g., miRNAs, lncRNAs), further modulates transcriptional landscapes to maintain stemness and reshape the TME, thereby reinforcing resistance to chemotherapy
At varying time points (0, 2, 5, 15, 30 min), purified Pt GSTF8 (8 M) and GSH (20 M) were added to an aliquot of the equilibration reaction and the resulting mixtures were incubated at 30 C for 30 min at 1200 rpm using a 3 mm shaking diameter before extraction with 2 vol of 75% methanol in H 2 O, 1 mM EDTA, 0.3% hydrochloric acid
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