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Call your healthcare provider if you experience: persistent vomiting or inability to keep fluids down severe abdominal pain signs of dehydration (dry mouth, dark urine, dizziness) severe allergic reactions (rash, swelling, difficulty breathing) Your clinician can offer strategies or consider dose adjustment if symptoms persist or interfere with daily life

Importantly, localized increases in GLP-1, such as that occur in the gut and portal vein, often have a more profound effect than systemic elevations, emphasizing the therapeutic potential of targeting regional activity rather than relying solely on systemic concentrations

Advancing research will undoubtedly add to this outstanding list of benefits

Promoting it can lead to eating disorders, body dysmorphia and drug use