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Hemolysis assay The various concentrations of D-CuP solution or hydrogel extract (G or G/D-CuP) (500 L) and 2% (v/v) red blood cells (RBC) suspension (500 L) were added to a 1.5 mL tube as sample groups
Clinical studies show it's well-tolerated even with long-term daily use, with adverse events limited to occasional mild skin irritation in sensitive individuals
Phase IIIII clinical trials are evaluating checkpoint blockade in combination with TGF- pathway inhibitors or antiangiogenic agents to normalize the vasculature and relieve T-cell exclusion
Zhu Y, Zhang JL, Yan XJ, Ji Y, Wang FF
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