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These agents draw water into the intestinal lumen, softening stool and stimulating motility
doi: 10.1016/j.molimm.2019.09.021 115 BourantasCVZanchinTSakellariosAKaragiannisARamasamyAYamajiKet al
Practical adjustments may also make symptoms easier to track and discuss
Three peer-reviewed, published human clinical trials show: ~18% Reduction in caloric intake at a subsequent meal, with measurable increases in GLP-1 and other satiety hormones (640% for GLP-1, 600% for CCK, and 170% for PYY over baseline) 23 Significant Hunger reduction in men during a 24-hour fast 24 30% Hunger reduction, 40% reduction in food cravings, and 14% fewer calories consumed in women during a 24-hour fast 25 No statistically significant adverse effects were reported across the three trials
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