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Metformin, alone or combined with cisplatin, downregulates NRF2 to counteract chemoresistance, while MSU38225, DHT, and Baicalin suppress NRF2 activity to disrupt redox adaptation in tumors
Weight management research explores compounds that influence energy balance, fat storage, and metabolic regulation
It targets not just one, but several core mechanisms of aging simultaneously: telomere maintenance, epigenetic regulation, oxidative stress resilience, immune recalibration, and circadian rhythm restoration [1]
The researchers used antisense oligonucleotide approaches to reduce NNMT specifically in adipose tissue
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