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For severe hypertriglyceridemia (500 mg/dL), fibrates or prescription omega-3 fatty acids (icosapent ethyl) remain first-line to prevent pancreatitis, though GLP-1 therapy may provide additional benefit in appropriate patients

Foster C, Baki J, Nikirk S, Williams S, Parikh ND, Tapper EB

Their abnormal proliferation causes synovial thickening, increased inflammation, and joint damage [237, 238]

In the posterior cortex, a reduction in DCFH levels was observed in the VPA+LipRSV group compared to the VPA group, suggesting that LipRSV treatment partially attenuated ROS production in this region

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