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In addition, the small leucine-rich repeat proteoglycan of bone extracellular matrix tissue biglycan, which is correlated with an aggressive phenotype of osteosarcoma, supported tumor growth and induced resistance to chemotherapy drug doxorubicin by forming a complex with IGF-1R leading to activation of the IGF-1R signaling pathway in human osteosarcoma cell line MG63 (37)
"Thymosin beta 4 promotes dermal wound repair." Journal of Investigative Dermatology
In rare cases, serious risks can occur, such as thyroid tumors, gallbladder disease, or medullary thyroid carcinoma
In addition, we describe the importance of accurate target (GLP-1 receptor) tissue expression analysis
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