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When used in topical formulations, the most commonly reported issues are localised and mild, and may include: Skin irritation or redness at the site of application Contact dermatitis in individuals with sensitive skin or known peptide sensitivities Scalp itching or tingling , which may be transient The following precautions are advised: Avoid application to broken, inflamed, or irritated skin , and keep the product away from the eyes and mucous membranes
Ghosh S, Masri F, Comhair S, Andreadis A, Swaidani S, et al: Nitration of proteins in murine model of asthma
Clin Rev Allergy Immunol 24:253-262, 2003
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