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Naganuma A, Nozaki A, Tanaka T, Sugiyama K, Takagi H, Mori M, Shimotohno K & Kato N (2000) Activation of the interferon-inducible 2-5-oligoadenylate synthetase gene by hepatitis C virus core protein

Plasma glucose also tended to decrease during the first 48 h (162126 mg/dl), accompanied by a parallel decrease in plasma insulin levels (184118 pmol/L) consistent with the insulinomimetic effects of GLP-1

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These modalities enhance GLP-1 sensitivity , preserve lean muscle mass , and reduce inflammation and visceral fat (fat around the organs (especially belly)a synergy shown to amplify metabolic benefits (PMC)